BERNARD, CLAUDE. Introduction à l'Étude de la Médecine Expérimentale. 400 pages, including half-title. 8vo, 213x131 mm, contemporary 1/4 sheep gilt, spine faded and scuffed, cover edges rubbed; intermittent foxing, particularly heavy at beginning and end, upper outer corner excised from front endleaf. Paris, London, Madrid, New York, & Leipzig: J. B. Baillière et Fils et al., 1865 [i. e., 1866]
first edition, first issue, with Crété imprint on verso of half-title and 5-city imprint on title, but later state with publisher's 48-page catalogue bound at end dated May 1866. "Probably the greatest classic on the principles of physiological investigation and of the scientific method as applied to the life sciences"--Garrison-Morton 1766.501. Norman 208; PMM 353.
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