OSLER, WILLIAM, Sir. The Principles and Practice of Medicine. 19 charts and 5 illustrations in text. xvi, [2], 1079, [7], 8 pages, including 3 ad leaves at end followed by publisher's catalogue dated June 1892. 8vo, 235x151 mm, publisher's 1/4 leather, spine rubbed, ends chipped, front cover detached, rear joint worn and starting, cover corners worn through; few ink blots on fore edges negligibly showing internally, contents otherwise clean. Signature of the physician, medical researcher, and Nobel laureate George R. Minot (1885-1950) on front free endpaper. New York: D. Appleton and Company, 1892